Epithalon 10mg

Epithalon 10mg

CAS (Pre-validation):307297-39-8

Molecular Weight (Pre-validation):390.35 g/mol


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Epithalon
Scientific Overview, Mechanism, Clinical Use and Evidence
 
Scientific Overview
 
Epithalon is a synthetic tetrapeptide analog of epithalamin, studied for potential influence on telomerase activation, pineal regulation, circadian rhythm support, and cellular longevity. Longevity medicine frameworks often explore Epithalon for its theoretical role in genomic stability and age-associated biological decline.
Mechanism of Action
 
Proposed mechanisms include:
 
•  Telomerase activation in vitro
•  Modulation of pineal gland signaling
•  Influence on melatonin secretion
•  Regulation of oxidative stress pathways
Biological and Clinical Effects
 
Preclinical data indicate telomere stabilization, improved stress adaptation, and circadian rhythm modulation. Limited human data suggest potential influence on aging-related biomarkers, though large-scale trials are lacking.
Time of Use / Treatment Duration
 
Short cyclic protocols (10–20 days) are commonly described, repeated semiannually or annually depending on clinical framework. Continuous long-term daily administration is not standard practice. Monitoring may include sleep quality, inflammatory markers, and metabolic labs.
Safety, Tolerability, and Precautions
 
Generally well tolerated in small human trials. Long-term safety data are limited.
Detailed References
Khavinson V, et al. (2003). Peptide regulation of gene expression and telomerase activity in aging. Bulletin of Experimental Biology and Medicine, 136(5):495–497.
 
Khavinson V, et al. (2007). Epitalon activates telomerase in human somatic cells. Bulletin of Experimental Biology and Medicine, 144(6):823–825.
 
Anisimov VN, et al. (2003). Effect of Epitalon on lifespan and spontaneous tumor incidence in mice. Experimental Gerontology, 38(4):343–349.
 
Khavinson V & Morozov VG. (2003). Peptide bioregulation of aging and longevity. Neuroendocrinology Letters.
 
LaValle J. The Complete Guide to Peptides. Longevity peptide discussion and circadian biology integration.
 
Epithalon
Posology (Clinical Practice–Oriented)
Protocols described in longevity medicine settings include:
•  5–10 mg daily, administered subcutaneously
•  Typical cycle duration: 10–20 consecutive days
•  Some protocols repeat 1–2 cycles per year
Use should remain limited to controlled or physician-supervised settings.
Clinical Practice Framing
Epithalon should be framed within cellular longevity research, emphasizing evidence-informed and biomarker-guided application rather than anti-aging claims.
The peptides described in this material are intended strictly for research purposes only. They are not approved for human or veterinary use, clinical application, diagnosis, treatment, or prevention of any disease.
Any research involving these compounds must be conducted in compliance with applicable laws and regulations in the country where the research is performed, including prior approval by a duly constituted Ethics Committee or Institutional Review Board (IRB), where required.
RegenPept acts solely as a supplier of research-grade materials and assumes no responsibility or liability for the design, conduct, regulatory compliance, interpretation, or outcomes of any research involving these products.
Any dosage, administration protocols, or related information contained in this material are derived from publicly available scientific literature and are provided strictly for informational purposes. Such information does not constitute medical advice, therapeutic recommendation, or endorsement of any specific use by RegenPept.
Quantity

10 vials, unit

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